Paget’s Disease of Bone – Symptoms and Causes

Overview

Paget’s disease impacts bone health by disrupting the normal bone renewal process. In healthy individuals, old bone tissue gradually gets replaced with new bone. However, this disease interferes with this cycle, resulting in fragile and misshapen bones.

The condition most commonly affects the pelvis, skull, spine, and legs. In some cases, Paget’s disease can cause pain and other complications. However, many people with Paget’s disease do not experience any symptoms.

Age increases risk for Paget’s disease, as does having family members with the condition. The disease has become less common in recent years and tends to develop less severely.

Without treatment, complications can arise, including bone fractures, hearing loss, and nerve compression in the spine.

Paget’s Disease of Bone Symptoms

When symptoms do occur, they can vary depending on the location of the affected bones. Common symptoms of Paget’s disease include bone pain, joint pain, and headaches.

Additionally, some people may experience hearing loss or have a noticeable change in their posture.

Paget’s Disease of Bone Causes

The exact cause of Paget’s disease is not known. However, it is believed to be related to a viral infection in some cases. Genetics may also play a role in the development of this condition.

Diagnosing Paget’s Disease of Bone

To diagnose Paget’s disease, a doctor will perform a physical exam and order imaging tests. These tests may include X-rays, bone scans, and blood tests. In some cases, a bone biopsy may be necessary to confirm the diagnosis.

Treating Paget’s Disease of Bone

Treatment for Paget’s disease aims to relieve symptoms and prevent complications. Medications such as bisphosphonates are commonly used to help slow down the bone remodeling process.

Physical therapy and assistive devices may also be recommended to manage pain and improve mobility. If the affected bones are severely weakened, surgery may be necessary to stabilize or replace them.


Related Questions

Responses are AI-generated